Dapsone-Resistant Leprosy
نویسندگان
چکیده
منابع مشابه
Dapsone-resistant leprosy in Addis Ababa: a progress report.
Two hundred and twelve lepromatous patients, presenting with suspected dapsone-resistant leprosy in the 5-year period 1 973-77, were taken into trial treatment with dapsone. Clinically, 55% have been proven to be dapsone resistant and the remainder are continuing to respond to full dosage dapsone after 4·5 to 9 years. This clinical observation contrasts with results of the dapsone-sensitivity s...
متن کاملMalaria, leprosy and dapsone.
Although the preventive action of dapsone against P. falciparum malaria was known for many years, there was no report about the incidence of P. falciparum malaria in leprosy patients treated with dapsone, especially from areas of Southeast Asia where both leprosy and malaria are endemic. Therefore, two clinic-based malaria surveys were undertaken at a gap of 12 years, comprising 506 lepromatous...
متن کاملDapsone agranulocytosis in a leprosy patient.
Dapsone-induced agranulocytosis is a rare adverse effect. There are various reports of agranulocytosis in patients treated with dapsone for malaria prophylaxis and other dermatological diseases. However, this adverse reaction in leprosy is not often encountered. We describe agranulocytosis in a young patient who was taking dapsone (100 mg) for borderline-tuberculoid leprosy in a rural environment.
متن کاملLow dose dapsone therapy in lepromatous leprosy.
U n der the conditions of this s tudy, dapsone in d oses of 5 mg and 10 mg daily when ad ministered to p atients with lepromat ous leprosy is an ineffe ctive therapy in terms of killing and elimin ation of My co. leprae from human skin and b one marrow . A real danger of facili tating the emergence of resistant bacilli exists . Therefore , un til there is more evidence from long term therapeuti...
متن کاملUlcerating lepromatous leprosy in a patient with dapsone-resistant Mycobacterium leprae.
While u nder treatment with'dapso ne for lepromatous leprosy , a 5 0-year-old male Greek Cypriot presented with multiple widespread lesions of a bizarre type, many of them freely ulceTating. Iinically and histologically, peripheral nerves were little affected, but biopsy s mples of skin and ulcers contained enormous numbers of leprosy bacilli. M ouse footpad inoculation of the bacilli from skin...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1973
ISSN: 0035-9157
DOI: 10.1177/003591577306600708